Research highlights

Sharon Lewin on the Lancet seminar paper overviewing HIV infection

Prof Sharon Lewin video

Prof Gary Maartens, Prof Connie Celum and Prof Sharon Lewin, Department of Infectious Diseases, have published a seminar article in The Lancet, "HIV infection: epidemiology, pathogenesis, treatment, and prevention". Sharon gives an overview of the article, including her own area of pathogenesis, covering recent developments in immune activation and vaccine development. "No-one clears HIV spontaneously", she says, which is a very unusual feature for a virus. Treatments are now investigating latency, or how to 'wake up' dormant virus hidden within cells. #HIV also causes low level inflammation from immune activation, which contributes to chronic disease development. See The Lancet abstract.