Research highlights: investigating why bypass grafts & stents fail
Dr Anthony Dear, ACBD
Neointimal hyperplasia, an injury related vascular response, accounts for the occlusion and failure of up to 50% of bypass grafts and stents used in the treatment of coronary artery and
peripheral vascular disease and constitutes a considerable health and economic burden to the community. Recent research conducted in Dr Anthony Dear's lab at the Australian Centre for Blood Diseases in collaboration with Professor Robert Widdop, Monash Department of Pharmacology, suggests that ;"epigenetic" mechanisms may be involved in the neointimal hyperplasia response.